Effect of Canarium schweinfurthii leaf and pulp extracts on blood glucose levels in oral glucose load - induced hyperglycemia in Wistar albino rats

نویسندگان

چکیده

Canarium schweinfurthii is a common medicinal plant used as food and medicine in communities of central Uganda. Local herbalists commonly it the management diabetes mellitus type 2 with limited information on its effectiveness.  Study assessed hypoglycemic effect C. aqueous total crude leaf pulp extracts blood glucose levels Wistar albino rats. An experimental based laboratory-based study was conducted 18 groups each 6 oral load 2.5 mg/kg bwt to induce physiological hyperglycemia. Group 1 got mL distilled water; group received 10 glibenclamide, 3-18 varying doses respectively. Blood sugar were determined at different time intervals (fasting, 0, 30, 60, 90, 180, 240 min) using an automated glucometer. approved by relevant IRB. Both exhibited activity though less than glibenclamide drug since curves above control water. All had lower compared hence continued use local Central Key words: Schweinfurthii, levels, effect,

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ژورنال

عنوان ژورنال: Journal of Medicinal Plants Research

سال: 2023

ISSN: ['1996-0875']

DOI: https://doi.org/10.5897/jmpr2023.7310